The effects of lead exposure on the expression of IGF1R, IGFBP3, Aβ40, and Aβ42 in PC12 cells

Journal of Trace Elements in Medicine and Biology(2022)

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摘要
This study shows that lead can obviously down-regulate the expression of IGF1R and IGFBP3, lead and inhibitor can inhibit the proliferation of cells, promote the tendency of apoptosis, and damage the nervous system.
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关键词
Lead,PC12 cells,IGF1R,IGFBP3,Immunocytochemical staining,Western blot
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