Comment on: “Perioperative goal-directed therapy in high-risk abdominal surgery. A multicenter randomized controlled superiority trial”

•Generalized perioperative goal-directed therapy results in variable patient outcomes after high-risk abdominal surgery.•The effect of perioperative goal-directed therapy on outcomes in larger multi-center trials is still unclear.•In this large trial, an age-specific cardiac index algorithm did not improve outcomes after high-risk abdominal surgery.