Defining Potential Therapeutic Targets in Coronavirus Disease 2019: A Cross-Sectional Analysis of a Single-Center Cohort.

Nishkantha Arulkumaran,Timothy Arthur Chandos Snow,Adarsh Kulkarni,David Brealey,Hannah Rickman,Chloe Rees-Spear,Moira J Spyer,Judith Heaney,Edmund Garr,Bryan Williams,Peter Cherepanov,George Kassiotis,Michael Lunn,Catherine Houlihan,Laura E McCoy,Eleni Nastouli,Mervyn Singer

Critical care explorations（2021）

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摘要

Some therapeutic and prognostic biomarkers may be useful in identifying coronavirus disease 2019 patients who may benefit from specific immunomodulatory therapies, particularly interleukin-6. However, biomarker absolute values often did not discriminate between patients with mild and severe disease or death, implying that these immunomodulatory treatments may be of limited benefit.

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关键词

acute respiratory distress syndrome,coronavirus disease 2019,critical care,cytokine,immunomodulation,interleukin-6

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