Spontaneous fundus lesions in elderly monkeys: An ideal model for age-related macular degeneration and high myopia clinical research

•We applied multimodal imaging to examine fundus lesions in aged cynomolgus monkeys.•A part of the monkeys exhibited spontaneous drusen, tessellated fundus, and myopic CNV.•Elderly cynomolgus monkeys are a promising animal model for research on AMD and high myopia.•An optimal animal model helps elucidate the pathophysiology, and pathogenesis of fundus diseases.