Two-step irradiance provides less pain with similar efficacy in photodynamic therapy on chinese patients with moderate to severe acne

Hai-En Wu,Yong-Bin Liu,Liang Cui,Peng Qin,Gui-Juan Xu,Xiao-Dong Sun,Xian-Wei Han

PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE（2021）

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摘要

Two-step irradiance schedule (2-SIS) has been shown to significantly reduce pain during topical 5-aminolevulinic acid photodynamic therapy (ALA-PDT) on non-melanoma skin cancer (NMSC) and condyloma acuminatum (CA).1, 2 Few studies focused on 2-SIS pain control during PDT for acne.

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