Propofol modulates inhibitory inputs in paraventricular thalamic nucleus of mice

Peng-Fei Liu,Yan Wang,Rui Zhang,Ling Xu,Jin-Bao Li,Di Mu

Neuroscience Letters（2021）

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摘要

•Propofol hyperpolarized PVT neurons and decreased action potentials induced by depolarizing step-current injections in the PVT neurons.•Propofol prolonged sIPSCs and mIPSCs, and increased the mIPSCs frequency in the PVT neurons.•Propofol induced tonic inhibitory currents via GABAA receptors.

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关键词

Propofol,Paraventricular thalamic nucleus (PVT),sIPSCs,mIPSCs,Tonic currents

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