Tangutidines A–C, Three Amphoteric Diterpene Alkaloids from Aconitum tanguticum

Hao-Yi Li,Bing-Chao Yan,Li-Xin Wei,Han-Dong Sun,Pema-Tenzin Puno

Natural Products and Bioprospecting（2021）

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摘要

Three new diterpene alkaloids, tangutidines A–C ( 1 – 3 ), and four known alkaloids ( 4 – 7 ) were isolated from the whole plant of Aconitum tanguticum , from which amphoteric diterpene alkaloids ( 1 – 3 ) were obtained for the first time. The structures of 1 – 3 were elucidated by detailed interpretation of spectroscopic data, including MS and NMR data. All of them were evaluated for their cytotoxic activities. Graphic Abstract

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关键词

Aconitum tanguticum,Amphoteric diterpene alkaloids,Tangutidine,Cytotoxic activity

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