Planette: A Modular Phase Iia Multicenter Open-Label Study Evaluating The Atr Inhibitor Ceralasertib (Azd6738) In Atm Mutant Advanced Solid Tumors.

Wassim Abida, Elkhan Sanay,Natalia Lukashchuk,Andrew Pierce, Wessel de Graaf,Alan Lau,Vidalba Rocher Ros,Nisha Kurian,Graeme Parr,Bienvenu LoembE,Emma Dean,Rahul Raj Aggarwal

JOURNAL OF CLINICAL ONCOLOGY（2021）

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摘要

TPS189Background: Ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) are kinases that orchestrate cellular responses to DNA damage. ATM is primarily activated by D...

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