Prenatal environmental tobacco smoke exposure alters children’s cognitive control circuitry: A preliminary study

Amy E Margolis,David Pagliaccio,Bruce Ramphal,Sarah Banker,Lauren Thomas,Morgan Robinson,Masato Honda,Tamara Sussman,Jonathan Posner,Kurunthachalam Kannan,Julie Herbstman,Virginia Rauh,Rachel Marsh

Environment International（2021）

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摘要

•Prenatal environmental tobacco smoke (ETS) increases risk for attention problems.•The neurobiological effects of prenatal ETS are unknown.•Prenatal ETS alters the structure and function of frontostriatal control circuitry.•Smaller thalamic volume mediated effects of exposure on attention problems.•ETS and smoking in pregnancy confer similar risk on brain structure and behavior.

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关键词

Cotinine,Environmental tobacco smoke,Cognitive control,Attention,Frontostriatal circuit

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