Screening For Ros1 Fusions In Patients With Advanced Non-Small Cell Lung Carcinomas Using The Ventana Ros1 (Sp384) Rabbit Monoclonal Primary Antibody

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS(2021)

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摘要
Introduction: The development of several ROS1 inhibitors means that the importance of accurately identifying ROS1-positive lung cancer patients has never been greater. Therefore, it is crucial that ROS1 testing assays become more standardized. Areas covered: Based on primary literature, combined with personal diagnostic and research experience, this review provide a pragmatic update on the use of the recently released VENTANA ROS1 (SP384) Rabbit Monoclonal Primary Antibody. Expert opinion: This assay provides high sensitivity, so it is an excellent analytical option when screening for ROS1 fusions in patients with advanced non-small cell lung carcinomas.
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关键词
ROS1, lung carcinoma, immunohistochemistry, SP384, biomarker
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