Active MT1-MMP is tethered to collagen fibers in DDR2-containing remnants

Yunfeng Feng, Hao Cai,Xinxin Huang, Zhengli Li,Zhenfen Chi,Ri-Li Ge

Gene（2021）

引用 2|浏览7

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摘要

•MT-MMP interacts and colocalizes with DDR2 in multiple cellular domains.•MT1-MMP is a component of DDR2-containing remnants.•DDR2 positively regulates MT1-MMP activity.•Tethered MT1-MMP on collagen fibers remains active.

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关键词

DDR2,MT1-MMP,Collagen,DDR2-containing remnants,Metastasis

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