Rapid-Deployment Aortic Valve Replacement In High-Risk Patients: A Case-Control Study

JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH(2021)

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摘要
Introduction: Aortic valve stenosis is the most frequent cardiac valve pathology in the western world. In high-risk patients, conventional aortic valve replacement (C-AVR) carries high rates of morbidity and mortality. In the last few years, rapid-deployment valves (RDV) have been developed to reduce the surgical risks. In this work, we aimed to compare the mid-term outcomes of rapid-deployment AVR (RD-AVR) with those of the C-AVR in high-risk patients.Methods: This retrospective case-control study identified 23 high-risk patients who underwent RDAVR between 12/2015 to 01/2018. The study group was compared with a control group of 46 patients who were retrospectively selected from a database of 687 C-AVR patients from 2016 to 2017 which matched with the study group for age and Euro SCORE II.Results: RD-AVR group presented more cardiovascular risk factors. Euro SCORE II was higher in the RD-AVR group (P = 0.06). In the RD-AVR group, we observed significantly higher mean prosthetic size (P < 0.001). In-hospital mortality was zero in RD-AVR group versus 2 deaths in C-AVR group. Hospital stay was longer in the RD-AVR group with statistical significance (P = 0.03). In the group AVR with associated cardiac procedures, while comparing subgroups RD-AVR versus C-AVR, early mean gradient was lower in the first cited (P = 0.02). The overall mean follow-up was 10.9 +/- 4.3 months.Conclusion: The RD-AVR technique is reliable and lead to positive outcomes. This procedure provides a much larger size with certainly better flow through the aortic root. It is an alternative to C-AVR in patients recognized to be surgically fragile.
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关键词
Aortic Valve Replacement, Rapid Deployment Aortic Valve, Calcified Aortic Stenosis, EuroSCORE II
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