[Synthesis and characterization of human rotavirus A ( Reoviridae: Sedoreovirinae: Rotavirus: Rotavirus A ) virus-like particles].

S A Cherepushkin,V V Tsibezov,A G Yuzhakov, O E Latyshev,K P Alekseev, E G Altayeva,K M Khametova, G K Vorkunova, K A Yuzhakova,T V Grebennikova

Voprosy virusologii（2021）

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摘要

The technology for the synthesis of three-layer VLP consisting of VP2, VP4, VP6 and VP7 has been developed and optimized. The resulting VLP composition represents 6 serotypes of VP4 and VP7, which are most represented on the territory of Russia, and can be used for vaccine development.

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