FLIPPER: Predicting and Characterizing Linear Interacting Peptides in the Protein Data Bank

Alexander Miguel Monzon, Paolo Bonato,Marco Necci,Silvio C E Tosatto,Damiano Piovesan

Journal of Molecular Biology（2021）

引用 9|浏览6

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摘要

•IDPs/IDRs exhibit a wide diversity of binding modes.•LIPs are functional regions with specific structural features.•FLIPPER is an accurate and fast LIP predictor from PDB structure complexes.•Different types of LIPs can be identified depending on the interaction partners.•FLIPPER provides the largest high quality data set of LIPs.

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关键词

linear interacting peptides,intrinsic disorder,protein structure,binding modes prediction,machine learning

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