Quantitative and Qualitative Analysis of Blood-based Liquid Biopsies to Inform Clinical Decision-making in Prostate Cancer

Irene Casanova-Salas,Alejandro Athie,Paul C. Boutros,Marzia Del Re,David T. Miyamoto,Kenneth J. Pienta,Edwin M. Posadas,Adam G. Sowalsky,Arnulf Stenzl,Alexander W. Wyatt,Joaquin Mateo

European Urology（2021）

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摘要

Liquid biopsy applications derived from circulating tumor cells, circulating tumor DNA, and extracellular vesicles in prostate cancer have been proved to be useful for monitoring tumor genomic evolution, disease progression, and response to therapy. Although further clinical qualification is needed, liquid biopsies can contribute toward implementation of precision care.

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关键词

Prostate cancer,Genomics,Liquid biopsy,Circulating tumor cell,Circulating tumor DNA,Extracellular vesicles,Precision medicine

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