Tumour-regulated anorexia preceding cachexia
NATURE CELL BIOLOGY(2021)
摘要
norexia commonly develops in patients with advanced cancer and is closely associated with cachexia. A new study shows that anorexia emerges earlier than cachexia in both Drosophila and mouse tumour models and that tumour-derived humoral factors induce anorexia by systemically dysregulating neuropeptides in the brain.
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关键词
Cancer metabolism,Hormones,Metabolic diseases,Life Sciences,general,Cell Biology,Cancer Research,Developmental Biology,Stem Cells
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