Treatment effect variability in brain stimulation across psychiatric disorders: A meta-analysis of variance

Neuroscience & Biobehavioral Reviews(2021)

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摘要
•The potential for precision medicine in brain stimulation is unclear.•To evaluate the need, variability between active and sham conditions can be compared.•Greater variability would indicate a need for precision medicine.•Variability was only slightly increased for active compared with sham across modalities.•This increase was mostly driven by studies in schizophrenia.
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关键词
Heterogeneity in treatment response,Noninvasive brain stimulation,Transcranial magnetic stimulation,Transcranial direct current stimulation,Personalized treatment,Unipolar and bipolar depression,Schizophrenia spectrum disorder,Bipolar disorder,Obsessive–compulsive disorder
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