Sonic Hedgehog receptor Patched deficiency in astrocytes enhances glucose metabolism in mice

Linda Tirou,Mariagiovanna Russo,Helene Faure,Giuliana Pellegrino, Clement Demongin,Mathieu Daynac,Ariane Sharif,Jeremy Amosse,Soazig Le Lay,Raphaël Denis,Serge Luquet,Mohammed Taouis,Yacir Benomar,Martial Ruat

Molecular Metabolism（2021）

引用 6|浏览11

暂无评分

摘要

•Astrocytes exhibit differences in regulating the hedgehog signaling pathway.•Deletion of Ptc in Glast+ cells prevents body weight gain and insulin resistance.•Deletion of Ptc in Glast+ cells increases β oxidation.•Central hedgehog signaling participates in the regulation of whole-body metabolism.

查看译文

关键词

Hypothalamus,Astrocyte,Glucose,Aging,Obesity,Hedgehog

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要