Human sensory neurons derived from pluripotent stem cells for disease modelling and personalized medicine

Angelika Lampert,David L. Bennett,Lucy A. McDermott, Anika Neureiter,Esther Eberhardt,Beate Winner,Martin Zenke

Neurobiology of Pain（2020）

引用 20|浏览4

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摘要

•New techniques emerge to study peripheral sensory neurons in iPS-cell derived models.•Genetic pain syndromes, e.g. gain- and loss-of-function mutations in Nav-channels are helpful.•Individualized treatment for neuropathic pain can be identified with iPS-cell derived nociceptors.

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关键词

iPSC,Disease modelling,Pain,Peripheral neuron,Stem cell differentiation

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