347 Outcomes of patients undergoing extremely high complexity surgery (EHCS) for advanced ovarian cancer, a single centre review of practice

Introduction The surgical complexity score (SCS) divides surgical extent by score into 3 categories; Low (0–3), Intermediate (4–7) and High (8+). This study addressed patients whose surgery for advanced ovarian/peritoneal/tubal epithelial cancer (AOC) scored ≥12. The outcomes following such extensive surgery are poorly described in the literature. Methods A retrospective review of surgical and oncological outcomes of all patients diagnosed between 17/2/16–14/5/19 with AOC treated with a SCS of ≥12. Results 11 patients received EHCS over 38 months, mean age 58. Median SCS was 13 (Range 12–16). 10 patients had serous cancer (grade 1=1, grade 3=9) and 1 had carcinosarcoma. 7 patients (63.6%) underwent primary debulking surgery and 4 (36.4%) interval debulking. All patients required diaphragmatic surgery, six (54.5%) required splenectomy and five (45.5%) paracardiac node resection. Mean blood loss was 1838 ml, mean operating time was 489 minutes (range 323–613). Complete cytoreduction was achieved in 10/11 patients (91%), 1 patient had Conclusion Surgery involving EHCS is safe and feasible. Larger data collection is needed to better inform both patients and clinicians on expected outcomes.