An Exaggerated Monocyte-Derived Cytokine Response to Candida Hyphae in Patients With Recurrent Vulvovaginal Candidiasis.

Diletta Rosati,Mariolina Bruno,Martin Jaeger,Bart-Jan Kullberg,Frank van de Veerdonk,Mihai G Netea,Jaap Ten Oever

The Journal of infectious diseases（2022）

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摘要

Women affected by RVVC showed increased monocytes-derived cytokine production, which might contribute to an exaggerated vaginal immune response to Candida hyphae. RVVC patients show no defective Th-dependent adaptive immune response upon Candida stimulation.

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关键词

Candida albicans ,RVVC,cytokines,immune response,innate immunity,recurrent vulvovaginal candidiasis

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