Effect of Pretreatment Paracetamol & Aceclofenac on Postendodontic Pain : An In Vivo Study

Aim: The aim of thisin vivostudy is to compare the effect of pretreatment paracetamol & aceclofenac on postendodontic pain. Materials & Methodology: 90 patients were divided into three groups of 30 patients and were given medication 30 minutes before the beginning of the procedure. Preoperative medication includes Paracetamol, Aceclofenac, and Placebo tablets. When instrumentation was completed, the canals were dried using paper points & intracanal medicament placed. The access cavity was closed withprovisional restorative material. Patients were instructed to maintain a pain diary at 6, 12, and 24 hours. The data was statistically analyzed by one way ANOVA followed by Tukey’s post-hoc test. Results: The result showed that postoperative pain reduction by aceclofenac is better at 6 hours and 12 hours followed by paracetamol and placebo. Conclusion:It can be concluded that aceclofenac was better in postoperative pain reduction when administered preoperatively 30 minutes before the beginning of the procedure. Aceclofenac was associated with the lowest level of postendodontic pain followed by paracetamol.