Supplemental Information The miR-1792 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells
semanticscholar(2015)
摘要
1. SUPPLEMENTAL DATA Figure S1: Gemcitabine resistant cells are enriched for CSCs, related to Figure 1 Figure S2: Slow cycling cells possess CSC phenotype, related to Figure 2. Figure S3: miR-17-92 downregulation in spheres and in gemcitabine resistant cells, related to Figure 3. Figure S4: miR-17-92 overexpression impairs CSC phenotype, related to Figure 4. Figure S5: miR-17-92 targets* multiple members of Nodal/TGFb signalling, related to Figure 5. Figure S6: Knockdown of p21 or TBX3 inhibits cancer stem cell phenotype, related to Figure 6. Figure S7: In vivo overexpression of miR-17-92 reverses quiescence and chemoresistance, related to Figure 7 Table S1: Table of utilized primer sequences for real-time RT-qPCR
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