The main active components of Curcuma zedoaria reduces collagen deposition in human lung fibroblast via autophagy.

Sun Chun-Bin,Ying Yi,Wu Qin-Yi,Liu Yang,Yu Jing-Ze,Xing Hai-Jing,Zhang Si-Qi,Hou Jiong,Wen Jing,Liu Fei-Yu,Yan Jin-Yuan,Yuan Jia-Li,Zhong-Shan Yang

Molecular Immunology（2020）

引用 14|浏览7

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摘要

•Curcumin and curcumol weaken the content of collagen in TGF-β1-induced fibroblast overproliferation HLF.•Autophagy is promoted by curcumin and curcumol in HLF.•Autophagy is needed to reduce the collagen, blocking autophagy by inhibitor CQ caused collagen accumulation.

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关键词

Curcumin and curcumol,Fibroblast,Collagen deposition,Autophagy

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