Anti-LINGO-1 antibody treatment improves chronic stress-induced spatial memory impairments and oligodendrocyte loss in the hippocampus.

Chunmao Yang,Jing Tang,Xin Liang,Yingqiang Qi,Yanmin Luo,Yuhan Xie,Jin Wang,Lin Jiang,Chunni Zhou,Chunxia Huang,Yong Tang

Behavioural Brain Research（2020）

引用 4|浏览12

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摘要

•Chronic stress induces spatial memory impairment.•Loss of oligodendrocytes may be associated with the spatial memory impairment induced by chronic stress.•Anti-Lingo-1 treatment protects against chronic stress-induced oligodendrocyte loss.

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关键词

Stress,Spatial memory,Hippocampus,Oligodendrocyte,Anti-LINGO-1,Stereology

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