Long term immunogenicity and effectiveness of the 9-valent HPV vaccine in preadolescents and adolescents

Rodney Finalle,Sven-Eric Olsson, Teobaldo Herrera,Jaime Restrepo, Rudiwilai Samakoses,Julio Reina,Punee Pitisuttithum, Angels Ulied,Glenda Gray,Meera Varman,Pierre Van Damme,Daron Ferris,Stan Block,Jennifer McCauley,Oliver Bautista,Alain Luxembourg

Pediatrics（2019）

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摘要

Background: The pivotal Phase III immunogenicity study of the 9vHPV vaccine in girls and boys (age 9-15 years) was extended to assess long-term immunogenicity and effectiveness through 10 years post-dose 3. We describe the first interim analysis at month 72. Subsequent analyses are planned at months 96 and 126, respectively. Methods: Overall, 1272 subjects (971 females, 301 males) …

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