Genetic Strategies to Understand Human Diabetic Nephropathy: In Silico Strategies for Molecular Data-Association Studies.

DIABETIC NEPHROPATHY: METHODS AND PROTOCOLS(2020)

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摘要
Multiple genetic strategies are available to help improve understanding of diabetic nephropathy. This chapter provides detailed methodology for a single-nucleotide polymorphism association study and meta-analysis, using a protocol suitable for targeted SNP or genome-wide association studies, to identify genetic risk factors for diabetic nephropathy.
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关键词
Association, Diabetic nephropathy, Genome-wide, Imputation, Meta-analysis, Plink, RAREMETAL, Rvtests, SNP, Trend
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