A Dual-Sensing Thermo-Chemical ISFET Array for DNA-Based Diagnostics.
IEEE Transactions on Biomedical Circuits and Systems(2020)
摘要
This paper presents a 32 × 32 ISFET array with inpixel dual-sensing and programmability targeted for on-chip DNA amplification detection. The pixel architecture provides thermal and chemical sensing by encoding temperature and ion activity in a single output PWM, modulating its frequency and its duty cycle respectively. Each pixel is composed of an ISFET-based differential linear OTA and a 2-stage...
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关键词
Oscillators,Temperature sensors,Pulse width modulation,Sensitivity,Chemicals,Capacitors
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