CD21 low B cells in systemic sclerosis: A possible marker of vascular complications.

Ramona Marrapodi,Chiara Pellicano,Giovanna Radicchio,Giorgia Leodori,Stefania Colantuono,Andrea Iacolare,Antonietta Gigante,Marcella Visentini,Edoardo Rosato

Clinical Immunology（2020）

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摘要

•CD21low percentage of B cells are higher in SSc patients than healthy donor.•CD21low percentage is higher in SSc patients with visceral vascular damage.•VEGF increases in SSc patients with low CD21low percentage.•CD21low percentage is a marker of impaired angiogenesis and vascular damage.

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关键词

Systemic sclerosis,B cells,CD21low,Pulmonary arterial hypertension,Kidney

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