The association of coagulation indicators with in-hospital mortality and 1-year mortality of patients with sepsis at ICU admissions: a retrospective cohort study.

•A U-shaped relationship was found between APTT and 1-year mortality of patients with sepsis.•Increased INR in critically ill septic patients are related to greater in-hospital mortality and 1-year mortality of the patients.•Statistically significant interactions were found between the INR and hospital mortality and both age and indwelling arterial catheter, cardiac arrhythmia, ventilation, liver diseases, and peripheral vascular diseases.