Pimavanserin Versus Quetiapine For The Treatment Of Psychosis In Parkinson'S Disease And Dementia With Lewy Bodies

•Compared pimavanserin to quetiapine in the treatment of Lewy body-related psychosis.•Used time to discontinuation analysis as a real-world, pragmatic, primary outcome.•Found lower early and higher late discontinuation of pimavanserin compared to quetiapine.•Pimavanserin may be more clinically useful at promptly managing psychosis.•Patients may continue quetiapine long-term for secondary, delayed benefits.