A coefficient identification problem for a mathematical model related to ductal carcinoma in situ

STUDIES IN APPLIED MATHEMATICS(2019)

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摘要
We consider a coefficient identification problem for a mathematical model with free boundary related to ductal carcinoma in situ (DCIS). This inverse problem aims to determine the nutrient consumption rate from additional measurement data at a boundary point. We first obtain a global-in-time uniqueness of our inverse problem. Then based on the optimization method, we present a regularization algorithm to recover the nutrient consumption rate. Finally, our numerical experiment shows the effectiveness of the proposed numerical method.
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关键词
DCIS model,free boundary problem,inverse problems,regularization algorithm
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