RSM based engineering of the critical gelation temperature in magneto-thermally responsive nanocarriers

Azin Khodaei,Reza Bagheri,Hamid Reza Madaah Hosseini,Elham Bagherzadeh

European Polymer Journal（2019）

引用 6|浏览3

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摘要

•The LCST of pluronic F127 and F68 blends were studied on the surface of SPION as a smart drug carrier.•Oleic acid content, polymer/particle and F127/F68 ratio were considered as the effective parameters.•The quadratic model suggested by RSM was modified to optimize the oleic acid content.•The recommended model can be applied to estimate the LCST for various particulate systems.

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关键词

Magnetite nanoparticles,Lower critical solution temperature (LCST),Pluronic blend,Modeling

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