Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019.

Anette M Hammerum,Ulrik S Justesen,Mette Pinholt,Louise Roer,Hülya Kaya,Peder Worning,Sanne Nygaard,Michael Kemp, Marianne Engell Clausen,Karen Leth Nielsen,Jurgita Samulioniené,Mona Kjærsgaard,Claus Østergaard,John Coia,Turid Snekloth Søndergaard,Shahin Gaini,Kristian Schønning,Henrik Westh,Henrik Hasman,Barbara Juliane Holzknecht

EUROSURVEILLANCE（2019）

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摘要

We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44% belonged to this type.

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关键词

Enterococci,MLST,VRE,VVE,vanA,vanB

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