Chemotherapy-induced cognitive impairments: A systematic review of the animal literature
Neuroscience & Biobehavioral Reviews(2019)
摘要
•Chemotherapy initiates cognitive decline in some cancer patients.•Rodent research overcomes methodological constraints in clinical practice.•Most cytotoxic chemotherapy regimens disrupt short term memory.•Mechanisms include inflammation, oxidative stress and disrupted neurogenesis.•Chemobrain executive control procedures must be homogenised in the literature.
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关键词
Chemotherapy,Memory,Inflammation,Hippocampus and treatment
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