A physics-based framework for analyzing the resilience of interdependent civil infrastructure systems: A climatic extreme event case in Hong Kong

•A synthetic physics-driven framework for system-wide infrastructure resilience analysis is developed.•The synthetic physics-driven framework takes into account the interdependency effects of infrastructure systems.•A case study related to extreme weather events in Hong Kong is conducted to demonstrate the proposed framework.•The temporal-spatial heterogeneity of disruptive impacts of hazards on the performance of transportation system is identified.