A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

International Journal for Parasitology: Drugs and Drug Resistance(2019)

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摘要
Infections with parasitic nematodes are among the most significant of the neglected tropical diseases affecting about a billion people living mainly in tropical regions with low economic activity.
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关键词
Anthelminitics,Caenorhabditis elegans,Sinefungin,SL1 trans-splicing,HTS assay
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