TAU ACCUMULATION IN RHINAL CORTEX IS ASSOCIATED WITH MEMORY PERFORMANCE IN NON-DEMENTED YOUNG ADULTS WITH AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE

P2-452 TAUACCUMULATION INRHINALCORTEX IS ASSOCIATEDWITH MEMORY PERFORMANCE IN NONDEMENTED YOUNG ADULTS WITH AUTOSOMAL DOMINANTALZHEIMER’S DISEASE Justin S. Sanchez, Reisa A. Sperling, Francisco Lopera, Jean Augustinack, Alex Becker, Heidi IL. Jacobs, David Jin, Samantha Katz, Evelyn Luner, Kirsten Moody, Julie C. Price, Edmarie Guzman-Velez, Ana Baena, Enmanuelle Pardilla-Delgado, Kewei Chen, Eric M. Reiman, Keith A. Johnson, Yakeel T. Quiroz, Massachusetts General Hospital, Boston, MA, USA; Center for Alzheimer Research and Treatment, Brigham andWomen’s Hospital, Harvard Medical School, Boston, MA, USA; Grupo de Neurociencias, Universidad de Antioquia, Medellin, Colombia; Massachusetts General Hospital, Charlestown, MA, USA; Alzheimer Center Limburg, Maastricht University, Maastricht, Netherlands; University of Pittsburgh, Pittsburgh, PA, USA; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; University of Arizona, Tucson, AZ, USA; Arizona Alzheimer’s Consortium, Phoenix, AZ, USA; Department of Radiology, Division of Molecular Imaging and Nuclear Medicine, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA. Contact e-mail: justin.sanchez@mgh. harvard.edu