Trusting homeostatic cues versus accepting hedonic cues: A randomized controlled trial comparing two distinct mindfulness-based intervention components

•Mindfulness shows preliminary promise as an obesity treatment approach.•Further testing of distinct mindfulness-based strategies for weight loss is needed.•Relative efficacy of two mindfulness strategies for weight loss was tested.•Mindful decision-making was slightly more effective than homeostatic cue reliance.•Across groups, greater acceptance was associated with more weight loss.