PLASMA CERAMIDE CONCENTRATIONS PREDICT RISK OF CARDIOVASCULAR EVENTS

Jeffrey W. Meeusen,Leslie J. Donato,Sandra C. Bryant,Grant M. Spears,Linnea M. Baudhuin,Allan S. Jaffe

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2017）

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摘要

Background: Ceramides are lipids that accumulate in tissues during hyperlipidemia and inflammation. Plasma concentrations of ceramides predict cardiovascular death in patients with CAD. Risk conferred is independent of age, sex, hypertension, smoking, LDL-C and HDL-C. Our objective was to validate

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