Specific cellular accumulation of photofrin-II in EC cells promotes photodynamic treatment efficacy in esophageal cancer.

•Photodynamic therapy (PDT) is a light-based oncological treatment modality.•The concentration of photofrin-II in cells could be measured by high-performance liquid chromatography (HPLC).•The accumulation of photofrin-II in esophagus cancerous cells were significantly higher than that in non-cancerous cells.