ROS mediated antibacterial activity of photoilluminated riboflavin: A photodynamic mechanism against nosocomial infections.

Toxicology Reports(2019)

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摘要
•Riboflavin undergoes intersystem conversion under photoillumination.•Interacts with molecular oxygen and generates ROS.•Generated ROS disrupts E. coli cell membranes.•Ultimately killing E. coli.•Mechanism can be used to kill E. coli on hospital ware causing nosocomial infections.
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关键词
Riboflavin,Antibacterial,Nosocomial infection,ROS,Photodynamic therapy
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