Silibinin Inhibits Proliferation and Migration of Human Hepatic Stellate LX-2 Cells.

Devaraj Ezhilarasan,Jonathan Evraerts,Sid Brice,Pedro Buc-Calderon,Sivanesan Karthikeyan,Etienne Sokal,Mustapha Najimi

Journal of Clinical and Experimental Hepatology（2016）

引用 26|浏览12

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摘要

The present study shows that SBN retards the proliferation, activation and migration of LX-2 cells without inducing cytotoxicity and oxidative stress. The profound effects could be due to cell cycle arresting potential of SBN.

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AKR1C1,ARE,CDKI,CYP450,DMSO,DMEM,ECM,FBS,GAPDH,HMOX1,HSCs,NQO1,Nrf-2,PPIA,PPAR-γ,qPCR,ROS,SBN,TXNRD1

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