Lingo-1: a novel target in therapy for Alzheimer's disease?

Unraveling the causes underlying Alzheimeru0027s disease (AD) is certainly one of the greatest challenges of this century for researchers. With advances in medicine and technology, the world is experiencing a demographic shift towards a growing elderly population. With this increasingly ageing population, the number of individuals being affected by AD is booming. AD has a significant negative impact on the lives of the individuals with the disorder, as well as creating a significant social and economic burden for society. Although major advances have been established in our understanding of the molecular and pathological mechanisms underlying this devastating disorder during the last decades, the causes for neuronal degeneration and its treatment remain elusive.