Internalization of the pseudorabies virus via macropinocytosis analyzed by quantum dot-based single-virus tracking.
CHEMICAL COMMUNICATIONS(2018)
摘要
With the aid of the single-virus tracking technique and the quantum dot-labeling strategy, the internalization of the pseudorabies virus (PrV) has been visualized in real time. The results demonstrate that macropinocytosis can be considered as a major pathway for PrV entering HeLa cells, which facilitates the development of therapeutics for virus-triggered diseases.
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