Aicardi goutières syndrome is associated with pulmonary hypertension.

Laura A Adang,David B Frank,Ahmed Gilani,Asako Takanohashi,Nicole Ulrick,Abigail Collins,Zachary Cross,Csaba Galambos,Guy Helman,Usama Kanaan,Stephanie Keller,Dawn Simon,Omar Sherbini,Brian D Hanna,Adeline L Vanderver

Molecular Genetics and Metabolism（2018）

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摘要

While pulmonary hypertension (PH) is a potentially life threatening complication of many inflammatory conditions, an association between Aicardi Goutières syndrome (AGS), a rare genetic cause of interferon (IFN) overproduction, and the development of PH has not been characterized to date.

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关键词

Pulmonary hypertension,Interferons,Aicardi Goutières Syndrome

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