Reducing harms from treatment. Sixteen years of surgery of the axilla for screen-detected breast cancers in Italy.

Maria Grazia Lazzaretti,Antonio Ponti,Maria Piera Mano,Alessandra Barca,Denise Casella,Alfonso Frigerio,Livia Giordano,Paola Mantellini,Adriana Paduos,Sabina Pitarella,Alessandra Ravaioli,Mario Taffurelli,Mariano Tomatis,Nereo Segnan

The Breast（2018）

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摘要

•Invasiveness of axillary surgery decreased dramatically in the last two decades.•Completion ALND in N+ patients decreased since publication of the Z0011 paper.•Smaller size, low grade and ER + are inversely associated to completion ALND.•Sentinel lymph node biopsy in low risk DCIS shows large variation in use.

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关键词

Breast cancer,Ductal carcinoma in situ,Sentinel lymph node biopsy,Axillary lymph nodes dissection,Mammography screening,Overtreatment,Z0011 trial

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