Stereotactic Radiation for Ultra-Central Non-SmallCell Lung Cancer: A Safety and EfficacyTrial(SUNSET)

M. E. Giuliani,E. J. Filion, S. Faria, V. Kundapur, T. T. T. Vu, B. H. Lok,S. Raman,H. Bahig, J. M. Laba, P. Lang,A. Louie, A. Hope, G. Rodrigues, A. Bezjak, M. P. Campeau, M. Duclos,S. Bratman,A. Swaminath,A. Warner,D. A. Palma

Clinical Lung Cancer（2024）

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摘要

It is important to identify a safe dose-fractionation regimen for treating ultracentral tumors with SBRT. In addition, the data from this study may be informative in guiding future studies on the use of SBRT in treating malignancies within the mediastinum-for example, for salvage treatment of mediastinal lymph nodes for recurrent NSCLC or mediastinal oligometastases.

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关键词

Central,Dose-escalation,Hypofractionated,Phase 1/2,SBRT

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