A Randomized Phase II Study of Axitinib as Maintenance Therapy After First-line Treatment for Metastatic Colorectal Cancer.

Cristina Grávalos,Alfredo Carrato,María Tobeña,Mercedes Rodriguez-Garrote,Gemma Soler,José Mª Vieitez,Luis Robles,Manuel Valladares-Ayerbes, Eduardo Polo, Mª Luisa Limón,Mª José Safont,Eva Martínez de Castro,Pilar García-Alfonso,Enrique Aranda

Clinical Colorectal Cancer（2018）

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摘要

In our study, maintenance treatment with axitinib monotherapy showed a significant increase in PFS and a good safety profile. Axitinib should be further explored as a possible option for first-line chemotherapy maintenance treatment in patients with mCRC.

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关键词

Axitinib,First-line setting,Maintenance therapy,Metastatic colorectal cancer,Progression free survival

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