Evaluation of early-phase [ 18 F]-florbetaben PET acquisition in clinical routine cases.

Sonja Daerr,Matthias Brendel,Christian Zach,Erik Mille, Dorothee Schilling,Mathias Johannes Zacherl,Katharina Bürger,Adrian Danek,Oliver Pogarell,Andreas Schildan,Marianne Patt,Henryk Barthel,Osama Sabri,Peter Bartenstein,Axel Rominger

NeuroImage: Clinical（2017）

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摘要

•Early-phase [18F]-florbetaben uptake depicts a metabolism-like image•Strong relative quantitative and visual correlations of early-phase [18F]-florbetaben uptake with FDG images•A two-phase [18F]-florbetaben protocol might give combined neurodegeneration and amyloid pathology biomarker information•Early-phase [18F]-florbetaben PET could ultimately circumvent the need for an additional FDG-PET in the dementia work-up.

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关键词

PET,FBB,FDG,3D-SSP,p.i.,AD,SPECT,CBF,CBL,GLM,MNI,SUVR,VOI,PCC,R,L,FTLD,MCI,CN

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